Neurondocrine Sensitivity

[Scotty D.]

I have been reading up on the Neuroendocrine Theory of Antiaging at http://www.vrp.com. This is the theory of Vladimir Dilman, i.e "that aging is caused by a progressive loss of sensitivity of the hypothalamus and related structures in the brain to negative feedback inhibition".

I am always attracted to 'sensitizing' myself, though I wonder if being 22 years of age means that one should avoid taking Neuroendogenic sensitizing herbs, such as goat's rue and ginkgo biloba, as this may inhibit what hormonal growth is yet to occur.

The relevant articles are at www.vrp.com, in the Library under the Hypothalamus & Cell Resensitizers section. Whether one thinks encourging this effect is a good thing or not, the research is enjoyably informative.

[James Boelter]

I think you ought to lay a LOT more 'groundwork' into your research before doing anything drastic - although I understand this thread is part of that groundwork.

At 22, you have a loooooong way to go before you need to worry about 'antiaging' protocols. Eat right, manage stress, get enough sleep, train carefully and do some yoga, chi kung, or Warrior Wellness/Bodyflow on a regular basis, and most 'antiaging' nutritional/herbal protocols will be irrelevant to you until you hit your 60's. (Unless you want to pursue it as a clinical practice or are interested in it for its own sake, which would be pretty cool).

I will go read those articles more carefully though. It's better to know than not to know.

[Scotty D.]

It is the sensitation of the neuroendocrine system that is of interest to me in this field, not so much the antiaging aspect. I have had the experience that a number of substances can really flux or accelerate my proprioception, and although enjoyable, I am more interested in perfecting dietary habits that have the same effect, such as PnP seems to be doing to some extent.

I have tried a herbal brew with herbs named in the vrp.com articles, and the effect was very akin to the sensitive feeling one gets during sickness such as a flu, although it was in the reverse direction, i.e. peaceful and with some vigor.

Although I am happy to play with such stimulation, my desire would be to follow this direction with natural foods and dietary habits. I did notice, on soing some sensitivity experimentation yesterday, that eating a durian while sensitive had the result of no following low-point, and I assume this to be the high tryptophan levels in durian.

I am definitly interested in this info for it's own sake, so I would love to continue this thread on the scientific and experiential issues of the Neuroendocrine theory. It is an 'information barrier' I am quite drawn to chipping at, though I don't think it is the best bodily system to go as far as 'getting my hands all bloodied up'. So to rephrase my initial query, whereas the theory at hand suggests that inhibiting homeostasis of the neuroendocrine system results in growth, and achieving homeostasis potentially interupts aging, is one who has not achieved full growth at any serious risk in sensitizing their neuroendocrine system towards homeostasis, or for the perceptual benefits of being sensitized?